产品货号：
Z16798
中文名称：
ERBB4抗体
英文名称：
Anti-ERBB4 Antibody
产品规格：
50μl|100μl|150μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ERBB4 Antibody |
| 指标别名 | 4ICD;E4ICD;ERBB4;HER4;p180erbB4;s80HER4 |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | WB |
| 基因名称 | ERBB4 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | A synthetic peptide corresponding to a sequence at the N-terminus of human ErbB 4(35-51aa KLSSLSDLEQQYRALRK),identical to the related rat and mouse sequences. |
| 实际分子量 | 180KD |
| 成分 | 500μg/mL antibody with PBS，0.02% NaN3,1mg BSA and 50% glycerol. |
| 纯化方式 | Immunogen affinity purified. |
| 浓度 | 500μg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 12 months from date of receipt，-20℃ as supplied.6 months 2 to 8℃ after reconstitution.Avoid repeated freezing and thawing. |
| 背景资料 | ERBB4(V-erb-b2 avian erythroblastic leukemia viral oncogene homolog 4) also known as ONCOGENE ERBB4 or HER4,is an enzyme that in humans is encoded by the ERBB4 gene.The HER4/ERBB4 gene is a member of the type I receptor tyrosine kinase subfamily that includes EGFR,ERBB2 and ERBB3.The ERBB4 gene is mapped on 2q34.ERBB4 is a single-pass type I transmembrane protein with multiple furin-like cysteine rich domains,a tyrosine kinase domain,a phosphotidylinositol-3 kinase binding site and a PDZ domainbinding motif.Huang et al.(2000) reported that ERBB4 is enriched in the postsynaptic density and associates with PSD95.ERBB4 is a transmembrane receptor tyrosine kinase that regulates cell proliferation and differentiation.After binding its ligand,heregulin,or activation of protein kinase C by TPA,the ERBB4 ectodomain is cleaved by a metalloprotease.Ni et al.(2001)concluded that gamma-secretase cleavage of ERBB4 may represent another mechanism for receptor tyrosine kinase-mediated signaling. |
| Uniprot ID | Q15303 |
| 推荐配套试剂 | Biorab recommends Enhanced Chemiluminescent Kit with anti-Rabbit IgG (ZN1926) for Western blot,and HRP Conjugated anti-Rabbit IgG Super Vision Assay Kit (ZN1865) for IHC(P).*Blocking peptide可以联系我们购买。 |
| 基因名全称 | v-erb-a erythroblastic leukemia viral oncogene homolog 4(avian) |
| 蛋白名全称 | Receptor tyrosine-protein kinase erbB-4 |
| 推荐稀释比 | Western blot(WB) 1:500～2000 |
相关搜索：ERBB4抗体，ERBB4多抗，Anti-ERBB4 Antibody